Dr. Dowling studies how juvenile idiopathic arthritis (JIA), the most common pediatric rheumatologic condition and a major cause of childhood-onset joint damage, develops in children. He obtained his B.S. at Georgetown University and his M.D.-Ph.D. degree at Albert Einstein College of Medicine. In his current role as a Brinson Medical Research Fellow at Lurie Children’s Hospital and Northwestern University Feinberg School of Medicine, Dr. Dowling is building a biorepository of pediatric synovium, the tissue that lines the inside of the joint and is the main site of disease activity in JIA. Using these tissue samples, he is defining genetic signatures of synovial immune cells that may predict clinical outcomes and treatment responses for children with JIA. His overarching goal is to leverage immunogenomics toward the development of precision medicine approaches in JIA.
Samuel Dowling
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